Sterilization of polypropylene autosampler vials depends on the method used and the temperature involved.
Autoclaving (Steam Sterilization)
We do not recommend autoclaving our clear polypropylene autosampler vials (9502S-PP-Clear) or amber variants. Although polypropylene has a relatively high melting point (~130–171°C), these vials may warp or deform under the high heat and pressure of autoclaving (typically 121°C or higher). This can compromise vial integrity and dimensional accuracy, which is critical for autosampler compatibility.
Ethylene Oxide (EtO) Sterilization
Yes, ethylene oxide gas is a suitable method for sterilizing polypropylene vials, as long as the temperature does not exceed 120°C. EtO sterilization is a low-temperature process that is widely used for heat-sensitive plastics and is effective at eliminating microbial contamination without damaging the vial structure.
✅Summary
|
Sterilization Method |
Suitable for Polypropylene Vials? |
Notes |
|---|---|---|
|
Autoclaving |
❌ Not Recommended |
May cause warping or deformation |
|
Ethylene Oxide (EtO) |
✅ Yes, if ≤ 120°C |
Safe and effective for sterilization |
Additional Tips
- Always verify sterilization compatibility with your lab’s SOPs and regulatory requirements.
- If sterility is critical, consider pre-sterilized vials or sterile packaging options.
- Avoid dry heat sterilization, which can exceed safe temperature thresholds for polypropylene.
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